Pd catalyst-simple ligand**

Thioalkylation with disulphides (R1S2R2)

Pd catalyst complex ligand**

SN2/SNAr in CMR solvents*

Michael addition

SN2/SNAr in non CMR solvents*

Base metal catalysis - simple ligand**

Thioalkylation with low Mol.Wt. leaving group (RSCl)

Base metal catalysis –complex ligand**

Thio-ene/yne reaction