Ethos of Guides

In line with the green chemistry roundtables core values, these guides aim to assist chemists in making informed decisions when picking the most sustainable reagent for any transformation at hand.

The guides have been compiled by enthusiastic industrial multidisciplinary chemists who have scaled many of the methods.

While the guides are designed to promote green chemistry, the aim is also for them to serve as a convenient reference and as such are not limited to only those reagents considered ‘green’.

Good green chemistry requires the chemist to look across a range of factors before making the best choice. With the inclusion of information such as atom efficiency, ecotoxicology / toxicology profiles, safety issues, waste products, sustainable feedstocks, and more, we hope these guides give obvious promotion of some reagents compared to others. However, a holistic approach is encouraged. For example, if a ‘greener’ reagent gives a much lower yield or requires multiple steps the overall benefit may be limited (i.e higher footprint in the wider context) in contrast to an initially less green reagent.


The American Chemical Society Green Chemistry Institute’s Pharmaceutical Roundtable (“the Roundtable”) has created this Reagent Guide to inform and guide users towards greener reagents for various chemical transformations. The Roundtable has used reasonable efforts in collecting, preparing and providing quality information and material, but does not warrant or guarantee the accuracy, completeness, adequacy or currency of the information contained in the Reagent Guide. By downloading, viewing and utilizing information from the Reagent Guide visitors assume full responsibility for their own actions and any damages or liabilities that may result from the utilization of information obtained from the Reagent Guide. Should you have any questions or comments about the Reagent Guide or this disclaimer, please send an e-mail to This email address is being protected from spambots. You need JavaScript enabled to view it..
© 2015 Green Chemistry Institute Pharmaceutical Roundtable. All rights reserved.