Metals Analysis

Traditionally metal levels are measured by techniques like Atomic Absorption, ICP, and X-ray fluorescence. These techniques are not always amenable to running medium or high throughput screens for metal scavengers. A number of techniques like fluorescence and HPLC following derivatisation / complexation are becoming more commonplace to rapidly analyse large numbers of samples for metal content.

OPRD, 2013, 17, 108–113 Rapid Analysis of Residual Palladium in Pharmaceutical Development Using a Catalysis-Based Fluorometric Method

RSC Catalysis Series (2015), 21 (New Trends in Cross-Coupling), 779-810 Palladium detection techniques for active pharmaceutical ingredients prepared via cross-couplings

© 2015 Green Chemistry Institute Pharmaceutical Roundtable. All rights reserved.