O-Dealkylation Reagents

Full Review

Boron/Aluminum reagents (Lewis acids)
Trimethylsilyl iodide
Hydrogenolysis – metal catalysis with H₂
Oxidation DDQ/CAN
Acids
Thiols/Methionine
Metal Halides
Biocatalysis

Light Touch Review

Metal –catalysed ether cleavage
Iodocyclohexane
Phosphine reagents
Amine bases /alkoxides
Hydride reagents – LiAlH₄/DIBAL/Selectride
Thermal Methods